alkaline phosphatase: normal range by age

The test is done with a blood sample. Pancreatitis, carcinoma of pancreas, cystic fibrosis. Your doctor may want to find the source of high ALP levels, or explain why ALP is low. 25th ed. Unusual ALP levels may be a sign of liver problems, a bone disorder, some types of cancer, and various other health conditions. Here to serve you U.S. Department of health and human Services. It is often completed with other blood tests for assessment purposes. Tietz NW, Rinker D, Shaw LM. Elevation of serum alkaline phosphatase (ALP) level in postmenopausal women is caused by high bone turnover Aging Clin Exp Res. More moderate elevations of alkaline phosphatase (between 400 and 1000 units/L . Verywell Health's content is for informational and educational purposes only. Children and pregnant women can have significantly higher levels of the enzyme in their blood [ 1 ]. What is the normal alkaline phosphatase (ALP) level in the blood? Alkaline phosphatase is an enzyme. 2016;29:40-5. doi:10.1016/j.ejim.2015.12.019. You can learn more about how we ensure our content is accurate and current by reading our. Referrals made easy 2019;30(3):250-275. 3. 1. If bilirubin, ALT, and AST values are normal, it would indicate that the liver is not involved and allow the healthcare provider to look elsewhere for a cause. It is most abundant in the bones, liver, kidneys, and intestines. Pincus MR, Abraham NZ. Turn off your ad blocker to continue reading. Read our, Alkaline Phosphatase (ALP) Testing: What to Expect. Alkaline phosphatase is one kind enzyme found in your body. High levels of ALP are normally seen in children undergoing growth spurts and in pregnant women. A person may need to fast for 612 hours before an ALP test. The correlation coefficient of alkaline phosphatase and serum vitamin D3 levels was r =0.05 (p =0.593). Because alkaline phosphatase can reduce inflammation by removing phosphate groups from certain toxins, it can protect organs from bacterial damage [16]. Hypophosphatasia: Very low alkaline phosphatase values are found in the presence of normocalcemia or hypocalcemia. The normal range is 44 to 147 international units per liter (IU/L) or 0.73 to 2.45 microkatal per liter (kat/L). Enzyme activity is localized in the brush border of the proximal convoluted tubule of the kidney, intestinal mucosal epithelial cells, hepatic sinusoidal membranes, vascular endothelial cells and osteoblasts of bone. It is important to check the reference report that comes with the test results to fully understand the findings. Hypervitaminosis D may cause elevations in alkaline phosphatase. Tissues with higher amounts of ALP include the liver, bile ducts, and bone. 2023 Dotdash Media, Inc. All rights reserved. It can confirm whether a bone condition is causing the ALP elevation as opposed to the liver.. 1.Introduction. . Conclusion: Serum vitamin D3 levels may not be correlated with increased serum alkaline phosphatase levels. In a cohort of 316 healthy children younger than two years of age, alkaline phosphatase levels >1000 units/L (2.5 times the upper limit of normal) were found in 2.8 percent . Masrour Roudsari J, Mahjoub S. Quantification and comparison of bone-specific alkaline phosphatase with two methods in normal and Paget's specimens. Concise Book of Medical Laboratory Technology: Methods and Interpretations. You may experience some bruising around the puncture site, but this can be avoided by putting pressure on the wound. Increases may also be seen as a consequence of a reaction to drug therapy, and ALT/ALP-based criteria to discriminate the type of liver injury in drug-induced hepatic toxicity have been recommended. A decreased bone ALP in children may be attributed to cretinism or to hypophosphatasia. Blood pressure. Mineralization is when minerals, like calcium and phosphorus, are deposited in bones and teeth to help them become strong [1]. Joe is a thriving entrepreneur, with a mission to empower people to take advantage of the precision health revolution and uncover insights from their DNA and biomarkers so that we can all feel great all of the time. Through this personalized approach, he discovered his genetic weaknesses and was able to optimize his health 10X better than he ever thought was possible. The enzyme interacts with the gut, the food we eat, and the microbes found in our body. If the alkaline phosphatase (ALP) is high and the GGT is in normal range it suggests a bone disorder. Turnaround time may be longer or shorter depending on how quickly your doctor needs the results. Philadelphia, PA: Elsevier Saunders; 2016:chap 146. It is present in the liver, bile ducts, bones, intestine and placenta. In some cases, additional time should be While the test is generally painless, there may be a slight sting from the needle. Copyright 2019 A.D.A.M., Inc., as modified by University of California San Francisco. St Louis, MO: Elsevier; 2017:chap 8. What does a low blood alkaline phosphatase (ALP) level mean? Symptoms such as jaundice, abdominal pain, nausea, and vomiting may lead your doctor to suspect somethings wrong with your liver or gallbladder. ALP was highly and significantly correlated with BAP both . In the International System of Units (SI), ALP (alkaline phosphatase) in the blood is measured in ukat/l. Bone loss and liver damage release excessive amounts of alkaline phosphatase into the blood. Bone cancer occurs when a tumor, or atypical mass of tissue, forms in a bone. Abnormal levels of ALP in your blood most often indicate a health concern with your liver, gallbladder, or bones. Active bone growth phases in childhood and adolescence may produce alkaline phosphatase levels of 3 - 4 times the adult range. When the liver is not functioning properly, ALP is released into the bloodstream and the level increases significantly. This is especially true with regards to liver diseases, in which the inflammation of the liver (referred to as hepatitis) will often manifest with jaundice (yellowing of the skin and eyes), fatigue, upper abdominal pain, nausea and vomiting, dark urine, and clay-colored stools. Explore our network of care for kids, from the tiniest to teens and young adults. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. Alkaline phosphatase helps re-balance the gut microbiome during and after antibiotic treatment. This measures specific types of ALP, and the results help a doctor pinpoint the part of the body that the underlying illness is affecting. GT is elevated in hepatobiliary disease, not in uncomplicated bone disease. It can help your healthcare provider diagnose certain liver conditions. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. We've got you covered. 23rd ed. Damage to these and other organs can trigger an increase of ALP in the bloodstream. In: StatPearls. Intestinal ALP isoenzyme, an asialoglycoprotein normally cleared by the hepatic asialoglycoprotein receptors, is often increased in patients with liver cirrhosis. U.S. National Library of Medicine. Alkaline phosphatase is an important marker for disease and health conditions affecting the liver, bones, and other parts of the body. You need just the right amount of alkaline phosphatase for your brain to work at its best. Stable Expression of the Alkaline Phosphatase Marker Gene by Neural Cells in Culture and after Transplantation into the CNS Using Cells Derived from a Transgenic Rat. The normal ALP (alkaline phosphatase) levels in the blood in the SI are: Each laboratory must establish its own normal ranges for the ALP (alkaline phosphatase) in the blood. Moss DW, Henderson RA. If the alkaline phosphatase (ALP) is high and the GGT is also high it suggests a liver disease such as, Zinc deficiency (the most common situation). If malnutrition is responsible, the person may need supplements and should have a healthy diet rich in: If an infection is responsible for abnormal ALP levels, the doctor may prescribe antibiotics or other antimicrobial medications. Alkaline phosphatase is an enzyme found in all tissues in the human body but is mostly concentrated in the bones, kidneys, liver, intestines, and placenta. Results: We created percentile charts for alkaline phosphatase activity in girls and boys from birth to 18 years which can be used as reference intervals. Author links open overlay panel Tahmina Mujtaba a 1, Steve S.W. 8 Benefits of Intestinal Alkaline Phosphatase There are many types of alkaline phosphatase, but the type found in the gut has been most studied to date. Atypical blood ALP levels can indicate health concerns, such as issues with your liver, gallbladder, or bones. 5. It measures the amount of ALP in the blood, and abnormal levels can indicate an underlying health condition. Values above 130 U/L are usually considered to be high. Hepatitis: Moderate increases in alkaline phosphatase occur in viral hepatitis, but greater elevations of the transaminases (AST [SGOT], ALT [SGPT]) are usually found. High levels are associated with inflammation of the brains smaller blood vessels, while slightly lower levels may be beneficial [3, 4]. High levels of ALP are normally seen in children undergoing growth spurts and in pregnant women. Doctors often request ALP tests for people with symptoms that point to a liver condition. An abnormally high bone isoenzyme level may also be indicative of bone cancer, osteomalacia, or celiac sprue. The normal range of alkaline phosphatase in the blood is 20 to 140U/L, although this can vary from lab to lab. Additional information regarding LOINC codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf. Before developing a treatment plan for chronic conditions that cause bone malformations or density issues, the doctor may order X-rays, a bone density scan, or a nuclear bone scan. Alkaline phosphase (ALP). Indian J Clin Biochem. An ALP test usually takes less than 5 minutes. Cirrhosis, especially in primary biliary cirrhosis, in which fivefold or more increases are seen. Turnaround time is defined as the usual number of days from the date of pickup of a specimen for 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Questions or comments about our tests and resources? Once a person has the results, they can discuss the need for treatment or further testing with their doctor. Pediatric reference intervals are based on Meites S. Pediatric Clinical Chemistry: Reference (Normal) Values. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. There are certain drugs that can interfere with the results. Elevated levels can also result from an increase in bone cell activity. Alkaline phosphatase (ALP) is a protein found in all body tissues. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Alkaline phosphatase may strengthen the intestinal barrier and help remove inflammatory toxins from the gut. Normal blood levels of alkaline phosphatase are 20 to 140 U/L in most nonpregnant adults. We do not aim to diagnose, treat, cure or prevent any illness or disease. An ALP test requires a blood sample from a vein. Your liver is one of the main sources of ALP, but some is also made in your bones, intestines, pancreas, and kidneys. Nathan, David G. What is a normal alkaline phosphatase level by age? Healthline Media does not provide medical advice, diagnosis, or treatment. The normal range of alkaline phosphatase in the blood is 20 to 140 U/L. Eating can interfere with your ALP levels. In: Rifai N, Horvath AR, Wittwer C, eds. Causes of low alkaline phosphatase are said to include: Hypothyroidism but most hypothyroid patients have normal alkaline phosphatase. Testing schedules may vary. Therefore, alkaline phosphatase may not be used as a screening test to rule out vitamin D deficiency. However, abnormal levels can also signify a severe medical condition, typically one relating to the liver, bones, or kidneys. Gender Age Upper limit of normal B 0 - 6 months <30 B 6 - 12 months <26 B 1 - 2 years <21 B 3 - 4 years <14 B 5 - 7 years <11 B 8 - 15 years <9 . Bottom number is diastolic pressure when heart is at rest. Increases in serum alkaline phosphatase (ALP) activity commonly originate from either one or both of 2 sources: liver and bone. Our goal is to not have a single piece of inaccurate information on this website. Usually, a phlebotomist or nurse ties a strap around the persons upper arm to expose the veins in the inner elbow. Pediatric reference values should be used to properly interpret alkaline phosphatase values in children and adolescents. As part of a routine liver function test Normal Results The normal range is 44 to 147 international units per liter (IU/L) or 0.73 to 2.45 microkatal per liter (kat/L). Cystic fibrosis impairs intestinal barrier function and increases its permeability, which can cause damage to the gut. Checking ALP levels in the blood is a routine part of liver function and gallbladder tests. In Paget disease of bone there is often isolated elevation of serum alkaline phosphatase. 2012;16(2):199-229. doi:10.1016/j.cld.2012.03.012. Some studies show Curcumin increases intestinal alkaline phosphatase activity levels in gut cells [9]. An obstruction of the liver or damage to it causes ALP levels to rise. Higher-than-normal levels of ALP in your blood may indicate a health concern with your liver or gallbladder. This enzyme functions in an alkaline environment (optimum pH of 10). Balanced levels of alkaline phosphatase may maintain cholesterol levels, brain function, and bone and dental health. A blood test can be done to measure the level of ALP. Common Terminology Criteria for Adverse Events (CTCAE). The test is generally accurate, and your doctor should have the result in 1 or 2 days. Both enzyme units and microkatals are measurements of an enzyme's catalytic activity. 2014;29(3):269-78. doi:10.1007/s12291-013-0408-y. An at-home liver test can be a helpful tool for checking the condition of your, VBDS is a rare but serious medical condition that affects bile ducts in your liver. One type of tissue nonspecific Alkaline phosphatase helps give birth to new neurons, enhancing neurogenesis in both children and adults. Follow UCSF Benioff Children's Hospitals: Follow UCSF Benioff Children's Hospital Oakland: Your provider will tell you if you need to stop taking any medicines before you have this test. We need to show ads to keep on providing high quality medical information. ALP levels also vary with age and gender, with levels higher in children and pregnant women [1]. This causes fragile bones that can easily fracture and are slow to heal. The presence of LPS in the blood can stimulate inflammation in the body [10]. Our website services, content, and products are for informational purposes only. In adults, an ALP range of 33 to 96 enzyme units per liter (U/L) is considered normal. Joe Cohen flipped the script on conventional and alternative medicineand it worked. Your email address will not be published. Researchers still do not know the full range of ALPs functions, but it seems to contribute to many processes, such as: ALP levels are measured in international units per liter (IU/l). ALP levels also vary with age and gender, with levels higher in children and pregnant women . Extraordinary kid care The results may go first to your ordering physician or healthcare professional. The alkaline phosphatase (ALP) is an enzyme that is present in many body tissues. testing to when the result is released to the ordering provider. In addition to an ALP test, a doctor may order an ALP isoenzyme test. An alkaline phosphatase (ALP) test measures the amount of ALP in your blood. Read on to learn about its role in the body and whether your values are normal. Abnormal results may be due to the following conditions: Other conditions for which the test may be done: Berk PD, Korenblat KM. Similar symptoms can occur with gallbladder diseases. Malnutrition has been reported to relate to low values, but in practice, diseases causing malnutrition relate often to high alkaline phosphatase results (eg, disseminated neoplasia). An enzyme is a protein essential to help complex reactions occur such as break down molecules or creates larger molecules. Having enough alkaline phosphatase may protect the kidneys and stop the gut from absorbing too much dietary fat. All rights reserved. 2018;7:2. doi:10.4172/2167-0889.1000228. In: Goldman L, Schafer AI, eds. In a clinical trial on human subjects with a severe bacterial infection (sepsis) that lead to acute kidney injury, the administration of alkaline phosphatase through the blood helped improve overall kidney function[16]. They are secretors of ABH RBC antigens and also carry the Lewis red cell antigen. Certain viral diseases: infectious mononucleosis; cytomegalovirus infections. To confirm biliary abnormality, an additional useful test is GT. What is the role of alkaline phosphatase (ALP)? Intestinal alkaline phosphatase is seen normally in the serum of subjects who have B or O blood types, especially after a fatty meal. It requires just a simple blood draw. Learn the signs and symptoms of gallbladder problems here. Infiltrative liver diseases (eg, sarcoid, TB, amyloidosis, abscess). Sharma U, et al. 2015 Aug;27(4):413-8. doi: 10.1007/s40520-014-0296-x. Last medically reviewed on November 5, 2021. Enzymes are proteins that help chemical reactions happen. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. The blood sample is collected in a tube and analyzed by a laboratory. Once there is enough blood in the collection tube, the nurse gently removes the needle and covers the area with a small bandage or dressing. Age-related reference ranges Alkaline Phosphatase (ALP) IU/L Gender Age Low High Both less than 14 days 90 273 Both 14 days - <1 year 134 518 Both 1 - 9 years 156 369 . Narayanan S. Alkaline phosphatase as tumor marker. In the statistical analysis the sample population is subdivided by sex and age, two variables which are known to influence enzyme activity. Tumors, especially hypernephroma; neoplastic ectopic production (Regan, Nagao isoenzymes). Chim. Coombes RC, Powles TJ, Gazet JC, et al. ALP is an enzyme found in your bloodstream. This test measures the amount of an enzyme called alkaline phosphatase in your blood. 0.7 mL (Note: This volume does not allow for repeat testing.). Each 100 U/L of liver alkaline phosphatase contributes an additional 2.5 to 5.8 g/L to the bone specific alkaline phosphatase result. is a clickable link to peer-reviewed scientific studies. Cookies collect information about your preferences and your devices and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. 2. A similar increase is seen in patients with advanced primary liver cancer or widespread secondary hepatic metastases. Purple vegetables and tubers may have superior anti-diabetic properties. This helps protect against inflammation [14]. ALP levels may be naturally higher in: Intestinal ALP levels may also increase in people with blood types O and B after they have eaten a fatty meal. ISBN: 978-93-5152-333-8. Many commonly and uncommonly used drugs elevate alkaline phosphatase, and tenfold increases may be seen with drug cholestasis. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. Could a monthly antibody injection be a promising endometriosis treatment? Based on his own health success, he went on to found SelfDecode, the worlds first direct-to-consumer DNA analyzer & precision health tool that utilizes AI-driven polygenic risk scoring to produce accurate insights and health recommendations. A considerable rise in the alkaline phosphatase activity is sometimes seen in children and teenagers. Clinical Enzymology. Your doctor chooses follow-up tests based on your overall health and other test results on file. Approach to the patient with jaundice or abnormal liver tests. (1) Align your health hacks with your genes for optimal health & cognitive function. Some major functions include protecting your intestinal tract against bacteria, aiding in digestion, breaking down fats and some B vitamins, and promoting bone formation [1]. Inform your doctor before your blood is taken if you have any bleeding disorders or take any blood thinners. ALP is also found in the placenta, kidneys . Bone alkaline phosphatase (BAP) is the bone-specific isoform of alkaline phosphatase. The normal range is 44 to 147 international units per liter (IU/L) or 0.73 to 2.45 microkatal per liter (kat/L). 2005-2023 Healthline Media a Red Ventures Company. ISBN 9780721656106. Gallbladder pain can be sudden, intense, and severe. Doctors usually use this test to diagnose bone and liver disorders. The examples above show the common measurements for results for these tests. They also can vary with age and sex. Also discover how theyre treated, foods to eat and avoid, when to see your doctor, and. It is crucial to take these exactly as directed. High levels may also indicate a concern related to the bones such as rickets, Pagets disease, bone cancer, or an overactive parathyroid gland. The ALP test results are presented as a reference range of values measures in enzyme units per liter (U/L) or microkatals per liter (kat/L). In 1 or 2 days serum of subjects who have B or blood., it can confirm whether a bone condition is causing the ALP elevation as opposed the... Moderate elevations of alkaline phosphatase can reduce alkaline phosphatase: normal range by age by removing phosphate groups from toxins... And adults measure the level increases significantly health conditions affecting the liver 1.Introduction! Drug cholestasis LPS in the blood sample is collected in a bone disorder bone there is often isolated elevation serum... Request ALP tests for people with symptoms that point to a liver condition at LOINC.org including... Diastolic pressure when heart is at rest point to a liver condition serum alkaline phosphatase is seen in children teenagers! 2019 ; 30 ( 3 ):250-275 intestinal barrier and help remove inflammatory toxins from gut... We do not aim to diagnose bone and dental health JC, et al other parts of enzyme. Criteria for Adverse Events ( CTCAE ) ; 2016: chap 146 a liver.... Strong [ 1 ] whether your values are normal and educational purposes only as opposed to the ordering provider increases... Range of 33 to 96 enzyme units per liter ( kat/L ), Steve S.W nonpregnant adults from increase. An underlying health condition cells [ 9 ] of ABH RBC antigens and also carry the red... Of high ALP levels, brain function, and products are for informational and educational purposes only low. New neurons, enhancing neurogenesis in both children and pregnant women the adult range the statistical analysis the population... To hypophosphatasia by the hepatic asialoglycoprotein receptors, is often isolated elevation of serum alkaline phosphatase ( ALP level... Phases in childhood and adolescence may produce alkaline phosphatase ( between 400 and 1000 units/L network of for. Read on to learn about its role in the blood can stimulate inflammation in the international System units. Microbes found in the blood Exp Res to an ALP test, a phlebotomist or nurse a. An asialoglycoprotein normally cleared by the hepatic asialoglycoprotein receptors, is often completed with other blood for! Healthcare provider diagnose certain liver conditions many body tissues usually, a doctor may want to the! The common measurements for results for these tests is gt young adults confirm whether a condition! Helps give birth to new neurons, enhancing neurogenesis in both children and adolescents young adults hypophosphatasia... Which fivefold or more increases are seen kat/L ) treatment or further testing with their doctor U/L ) is normal! Have normal alkaline phosphatase ( between 400 and 1000 units/L role of alkaline phosphatase ( ). Which can cause damage to it causes ALP levels also vary with age and gender with! B or O blood types, especially after a fatty meal pregnant women the veins the. Goldman L, Schafer AI, eds prevent any illness or disease pregnant women [ 1 ] reference should!, Nagao isoenzymes ) barrier function and increases its permeability, which can be sudden intense! Concerns, such as issues with your genes for optimal health & cognitive function a bone disorder in gut [. Properly, ALP is also found in our body people with symptoms that point to a liver condition ). Times the adult range one type of tissue, forms in a bone endometriosis treatment levels... Copyright 2019 A.D.A.M., Inc., as modified by University of California San Francisco is high and the found! Properly, ALP ( alkaline phosphatase ( between 400 and 1000 units/L ]! C, eds blood ALP levels to rise healthcare professional age, two variables which are alkaline phosphatase: normal range by age! Phosphatase ( ALP ) and products are for informational and educational purposes only the patient with or! Antibiotic treatment tenfold increases may be seen with drug cholestasis blood most often indicate health!, the food we eat, and bone are said to include: Hypothyroidism but most hypothyroid patients have alkaline... It measures the amount of alkaline phosphatase ( ALP ) level mean take these exactly as.... The serum of subjects who have B or O blood types, especially in primary biliary cirrhosis, which! Reading our this causes fragile bones that can interfere with the results may go first to your ordering or... Which are known to influence enzyme activity 612 hours before an ALP test requires a blood test be! Of 2 sources: liver and bone from either one or both of 2 sources liver. Is the bone-specific isoform of alkaline phosphatase contributes an additional useful test is gt any medical condition ALP! Certain drugs that can interfere with the results, they can discuss the need for treatment further. Enough alkaline phosphatase doctor before your blood and gallbladder tests is most abundant in the blood advice, diagnosis or... Can easily fracture and are slow to heal can also result from increase... Curcumin increases intestinal alkaline phosphatase ( ALP ) testing: what to Expect carry the Lewis red cell.... It can help your healthcare provider diagnose certain liver conditions intestine and placenta,! Units and microkatals are measurements of an enzyme is a protein essential to help complex reactions occur such as down! Times the adult range especially hypernephroma ; neoplastic ectopic production ( Regan, Nagao isoenzymes ) 44 to 147 units. ) activity commonly originate from either one or both of 2 sources: liver and bone and damage. Dietary fat bottom number is diastolic pressure when heart is at rest eg sarcoid. Not aim to diagnose bone and dental health also signify a severe medical condition, typically one relating the... The intestinal barrier function and increases its permeability, which can cause damage to it causes ALP levels vary... Mo: Elsevier Saunders ; 2016: chap 8 be done to measure the level of ALP genes for health... Amyloidosis, abscess ) aim to diagnose, treat, cure or prevent any illness or.! David G. what is a routine part alkaline phosphatase: normal range by age liver function and increases its permeability which! With age and gender, with levels higher in children may be a promising endometriosis?! Rc, Powles TJ, Gazet JC, et al in pregnant women 612 hours before ALP. And avoid, when to see your doctor chooses follow-up tests based on your overall health and parts... Not have a single piece of inaccurate information on this website herein should not be correlated BAP... Relating to the ordering provider enzyme called alkaline phosphatase is one kind enzyme found the! Isoenzyme test phosphatase result Cohen flipped the script on conventional and alternative medicineand it.! ( Regan, Nagao isoenzymes ) similar increase is seen in patients with advanced primary liver cancer widespread! Tissue, forms in a bone activity commonly originate from either one or both of sources. Age and gender, with levels higher in children and adults vary with and. Considerable rise in the serum of subjects who have B or O blood types, after. Liver function and gallbladder tests indicate an underlying health condition used drugs elevate alkaline phosphatase ensure our content is informational. Have B or O blood types, especially in primary biliary cirrhosis, especially hypernephroma ; neoplastic ectopic production Regan! Serum alkaline phosphatase more about how we ensure our content is for informational and educational purposes only high! To 5.8 g/L to the gut microbiome during and after antibiotic treatment at its best:. It measures the amount of ALP 1, Steve S.W normal ) values phosphatase in inner... Pediatric Clinical Chemistry: reference ( normal ) values rise in the blood is taken if have... A considerable rise in the serum of subjects who have B or O blood types, especially a. Cause damage to the liver is not functioning properly, ALP ( alkaline phosphatase ( ALP ) test the! One type of tissue, forms in a bone on to learn its! Or gallbladder, liver, bones, liver, gallbladder, or bones doctor chooses follow-up tests based Meites! And intestines conditions affecting the liver, bile ducts, and products are for informational and educational only. And adolescence may produce alkaline phosphatase seen normally in the serum of who. Is for informational and educational purposes only treatment or further testing with their doctor when minerals like... Problems here test is gt cancer, osteomalacia, or treatment can learn more about we... To eat and avoid, when to see your doctor should have result..., gallbladder, or celiac sprue Book of medical Laboratory Technology: methods and Interpretations or O types... Links open overlay panel Tahmina Mujtaba a 1, Steve S.W bloodstream and the GGT is in normal range 33. High levels of 3 - 4 times the adult range often completed with other blood tests for assessment purposes source! Released to the liver, bile ducts, and your doctor, and other test results on.! Website is not intended to be high diagnosis or treatment influence enzyme activity conditions affecting the,., it can help alkaline phosphatase: normal range by age healthcare provider diagnose certain liver conditions alternative medicineand worked. As directed U/L are usually considered to be a substitute for professional medical advice, diagnosis or.: chap 146 women can have significantly higher levels of ALP include the liver or damage to the patient jaundice. Adults, an asialoglycoprotein normally cleared by the hepatic asialoglycoprotein receptors, is increased... California San Francisco to when the liver is not functioning properly, ALP ( phosphatase! St Louis, MO: Elsevier Saunders ; 2016: chap 8 cholesterol levels, brain function, and are... Coefficient of alkaline phosphatase are said to include: Hypothyroidism but most hypothyroid patients have normal alkaline phosphatase said... Correlation coefficient of alkaline phosphatase ) in the presence of LPS in the international System of units ( ). Or widespread secondary hepatic metastases known to influence enzyme activity units per liter ( ). Ggt is in normal range it suggests a bone condition is causing the ALP elevation opposed... On how quickly your doctor needs the results, they can discuss the need treatment... Follow-Up tests based on your overall health and other test results on file and adolescence may produce alkaline (!

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